JMM Profile: Mycoplasma genitalium: a small, yet significant pathogen

Mycoplasma genitalium is characterized by a small genome and a lack of a cell wall, contributing to its unique biology. It is associated with reproductive tract infections, including non-gonococcal urethritis and pelvic inflammatory disease. It is nearly as common as chlamydia in most studies from high-income countries. The emergence of antimicrobial resistance in M. genitalium raises concern about the long-term efficacy of current therapeutic strategies. Understanding its genomic intricacies and pathogenic mechanisms is crucial for developing targeted interventions to address the growing public health impact of this elusive microbe.