Impact of Mechanical Circulatory Support on Exercise Capacity in Patients With Advanced Heart Failure

Janice Huang; Barry J. McDonnell; Justin S. Lawley; Jessica Byrd; Eric J. Stöhr; William K. Cornwell

doi:10.1249/JES.0000000000000303

Impact of Mechanical Circulatory Support on Exercise Capacity in Patients With Advanced Heart Failure

Janice Huang
, Barry J. McDonnell
, Justin S. Lawley
, Jessica Byrd
, Eric J. Stöhr
, William K. Cornwell^*

^*Corresponding author for this work

Research output: Contribution to journal › Article › peer-review

4 Citations (Scopus)

Abstract

Approximately 6 million individuals have heart failure in the United States alone and 15 million in Europe. Left ventricular assist devices (LVAD) improve survival in these patients, but functional capacity may not fully improve. This article examines the hypothesis that patients supported by LVAD experience persistent reductions in functional capacity and explores mechanisms accounting for abnormalities in exercise tolerance.

Original language	English
Pages (from-to)	222-229
Number of pages	8
Journal	Exercise and Sport Sciences Reviews
Volume	50
Issue number	4
DOIs	https://doi.org/10.1249/JES.0000000000000303
Publication status	Published - 1 Oct 2022

Keywords

Exercise intolerance
Heart failure with reduced ejection fraction
Left ventricular assist device
Maximal oxygen uptake
Oxygen cascade

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10.1249/JES.0000000000000303

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title = "Impact of Mechanical Circulatory Support on Exercise Capacity in Patients With Advanced Heart Failure",

abstract = "Approximately 6 million individuals have heart failure in the United States alone and 15 million in Europe. Left ventricular assist devices (LVAD) improve survival in these patients, but functional capacity may not fully improve. This article examines the hypothesis that patients supported by LVAD experience persistent reductions in functional capacity and explores mechanisms accounting for abnormalities in exercise tolerance.",

keywords = "Exercise intolerance, Heart failure with reduced ejection fraction, Left ventricular assist device, Maximal oxygen uptake, Oxygen cascade",

author = "Janice Huang and McDonnell, \{Barry J.\} and Lawley, \{Justin S.\} and Jessica Byrd and St{\"o}hr, \{Eric J.\} and Cornwell, \{William K.\}",

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year = "2022",

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AU - McDonnell, Barry J.

AU - Lawley, Justin S.

AU - Byrd, Jessica

AU - Stöhr, Eric J.

AU - Cornwell, William K.

N1 - Publisher Copyright: © Lippincott Williams & Wilkins.

PY - 2022/10/1

Y1 - 2022/10/1

N2 - Approximately 6 million individuals have heart failure in the United States alone and 15 million in Europe. Left ventricular assist devices (LVAD) improve survival in these patients, but functional capacity may not fully improve. This article examines the hypothesis that patients supported by LVAD experience persistent reductions in functional capacity and explores mechanisms accounting for abnormalities in exercise tolerance.

AB - Approximately 6 million individuals have heart failure in the United States alone and 15 million in Europe. Left ventricular assist devices (LVAD) improve survival in these patients, but functional capacity may not fully improve. This article examines the hypothesis that patients supported by LVAD experience persistent reductions in functional capacity and explores mechanisms accounting for abnormalities in exercise tolerance.

KW - Exercise intolerance

KW - Heart failure with reduced ejection fraction

KW - Left ventricular assist device

KW - Maximal oxygen uptake

KW - Oxygen cascade

UR - https://www.scopus.com/pages/publications/85137661947

U2 - 10.1249/JES.0000000000000303

DO - 10.1249/JES.0000000000000303

M3 - Article

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AN - SCOPUS:85137661947

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VL - 50

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EP - 229

JO - Exercise and Sport Sciences Reviews

JF - Exercise and Sport Sciences Reviews

IS - 4

ER -

Impact of Mechanical Circulatory Support on Exercise Capacity in Patients With Advanced Heart Failure

Abstract

Keywords

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