Extracellular Vesicles in Atherosclerosis Research

Jessica O. Williams, Cass Whelan, Jamie Nash, Philip E. James*

*Corresponding author for this work

Research output: Chapter in Book/Report/Conference proceedingChapterpeer-review

2 Citations (Scopus)
3 Downloads (Pure)

Abstract

The methodologies described in this chapter inform on how to incorporate extracellular vesicles (EV) in model systems to investigate their role in the initiation and progression of the atherosclerotic plaque. The section will cover application of EV in coagulation and thrombus formation, monocytic migration, and adhesion to endothelial monolayers. These methodologies can be used with EV isolated from any cell type and under any conditions.

Original languageEnglish
Title of host publication Atherosclerosis
PublisherSpringer
Pages349-359
Number of pages11
Volume2419
ISBN (Electronic)9781071619247
ISBN (Print)9781071619230
DOIs
Publication statusPublished - 2 Mar 2022

Publication series

NameMethods in Molecular Biology
Volume2419
ISSN (Print)1064-3745
ISSN (Electronic)1940-6029

Keywords

  • Atherosclerosis
  • Extracellular vesicles
  • Monocyte migration
  • Static adhesion
  • Thrombus formation

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