Abstract
Background and aim: To identify the distribution and explore the relationship between ACTN3 genotypes and power and body composition phenotypes.Subjects and methods: Case control and association studies were employed using a homogeneous group of players (n = 102) and a control group (n = 110). Power-related phenotypes were measured using the counter movement jump (CMJ) and body composition phenotypes by dual-energy X-ray absorptiometry (DXA). Statistics used were Pearson's chi-square, ANCOVA, coefficients of correlation and independent t-tests. Genotyping was carried out using polymerase chain reaction followed by enzymatic Ddel digestion.Results: Genotype proportions of players were compared with controls (p = 0.07). No significant genotype differences occurred between forwards or backs (p = 0.822) or within-forwards (p = 0.882) or within-backs (p = 0.07). Relative force and velocity were significantly larger in backs, power significantly greater in forwards; in body composition, all phenotypes were significantly greater in forwards than backs. Correlations between phenotypes were greater for the RX genotype (p = 0.050.01).Conclusions: Relationships between ACTN3 genotypes and power or body composition-related phenotypes were not significant. As fat increased, power-related phenotypes decreased. As body composition increased, power-related phenotypes increased.
Original language | English |
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Pages (from-to) | 19-27 |
Number of pages | 9 |
Journal | Annals of Human Biology |
Volume | 39 |
Issue number | 1 |
DOIs | |
Publication status | Published - 28 Nov 2011 |
Keywords
- α-actinin-3
- Body composition
- Power output
- Rugby union