Personal profile
Research interests
Dr Jess Williams is a Research Fellow in Cardiovascular Metabolism within CURIAD. Jess’ work focuses on the inflammatory progression of cardiovascular disease, looking at methods of disease prevention and novel treatment options. Jess is a Medical Pharmacologist by training and later obtained a British Heart Foundation funded PhD from Cardiff University’s School of Medicine’ focused on the role of uncontrolled inflammation in the co-morbidity between rheumatoid arthritis and cardiovascular disease. She has since completed postdoctoral research associate roles at both Cardiff University and Cardiff Metropolitan University.
Research Interests
Jess’ current work focuses on establishing novel methods to stop the progression of cardiovascular disease, with a focus on reducing inflammation. She is now working as a Research Fellow at Cardiff Metropolitan University, where her recent research, funded by the Stroke Association, focuses on using blood biomarkers to predict the risk of stroke in high-risk populations. This research assesses production and phenotypical analysis of populations of extracellular vesicles (EV) in high-risk cardiovascular patients. The project will assess EV reliability and usability as a predictive marker for stroke. Jess’ research also covers EV as a product, for example following blood product storage for transfusion, she is interested in the resultant effect of this process on cardiovascular outcomes.
Further to this Jess is involved in public health the collection of patient experience data, following a stroke to better understand the public’s perception of associated symptoms. It is hoped that applying a mixed methods approach will inform educational platforms to aid the public awareness of disease symptoms and foster a culture of taking ownership of modifiable cardiovascular risk factors.
Jess is also interested in the use of incorporating nutraceuticals in diet as a preventative measure to reduce cardiovascular burden. Her prior post-doctoral research focused on the use of omega-6 fatty acids to reduce inflammation association with atherosclerosis. She has more recently worked with flavonoids and carotenoids.
Jess is passionate about the patient voice in scientific research. To that end she is the Patient Public Involvement (PPI) lead for Stroke Hub Wales. Our mission is to ensure that the voices of experts by experience are at the heart of all stroke research carried out in Wales, creating an active partnership that allows true co-production of research. Recently, Jess has set up a new PPI group, which sits under the Centre for Activity and Wellbeing Research at Cardiff Met, which covers all aspects of Women’s Reproductive Health.
Expertise related to UN Sustainable Development Goals
In 2015, UN member states agreed to 17 global Sustainable Development Goals (SDGs) to end poverty, protect the planet and ensure prosperity for all. This person’s work contributes towards the following SDG(s):
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SDG 3 Good Health and Well-being
Collaborations and top research areas from the last five years
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Computational Fluid Dynamic Analysis of Fluid Motion and Volumetric Gas-Liquid Mass Transfer in Agitated Platelet Concentrate Storage
Pym, D., Davies, A. J., Williams, J. O., Saunders, C., George, C. E., Mason-Jones, A. & James, P. E., 8 Jan 2026, In: Biotechnology journal. 21, 1, e70177.Research output: Contribution to journal › Article › peer-review
Open Access -
Hypoxia stimulates blood–brain barrier disruption and systemic appearance of pro-coagulant, brain-derived extracellular vesicles: Implications in transient ischaemic attack patients
Raven, R. M., Williams, J. O., Whelan, C., White, J., Morris, K., Geen, J. & James, P. E., 5 Feb 2026, In: Journal of Cerebral Blood Flow and Metabolism.Research output: Contribution to journal › Article › peer-review
Open Access -
The Role of Extracellular Vesicles in Transient Ischaemic Attacks and Ischaemic Stroke: A Systematic Review
Raven, R. M., James, P. E., Morris, K. & Williams, J. O., 13 Mar 2026, In: Journal of Extracellular Biology. 5, 3Research output: Contribution to journal › Review article › peer-review
Open Access -
Enhanced O 2 availability in platelet concentrates stored for neonatal transfusion is independent of agitation: Evidence from direct oximetry and Fickian diffusion modelling
Pym, D., Grinberg, O., Davies, A. J., Williams, J. O., Saunders, C., George, C. E. & James, P. E., 28 Aug 2025, In: Vox Sanguinis. 120, 12, p. 1232-1241 10 p.Research output: Contribution to journal › Article › peer-review
Open Access1 Citation (Scopus) -
Micro-Rheology and Co-Stream Microfluidics Reveal Critical Contributions of Platelet Concentrate Components to Blood Platelet Integrity in Storage
Pym, D., Paul, A., Davies, A. J., Williams, J. O., Saunders, C., George, C. E. & James, P. E., 17 Dec 2025, In: BioNanoScience. 16, 1, 25.Research output: Contribution to journal › Article › peer-review
Open Access