Personal profile
Research interests
Chris is a Reader in Exercise & Cardiovascular Physiology within the Cardiff School of Sport & Health Sciences, and leads the Clinical Application & Translation Research & Innovation Group within CURIAD.
The global aim of his research programme is to examine how regular exercise and physical activity can effectively prevent, manage and treat cardiometabolic disease across the lifespan. His research focusses primarily on the chronic and acute effects of exercise on peripheral, central and cerebral artery function and haemodynamics in a diverse range of populations, including paediatric, elite athletic, ageing and high-risk disease states. Chris has extensive track record in the design and administration of exercise interventions in a variety of clinical populations and has lead several randomized controlled exercise trials. He also has in-depth expertise in advanced imaging techniques, including ultrasound and MRI, for early detection of occult cardiometabolic disease and evaluation of the therapeutic effects of distinct exercise training modalities, heat therapy, water immersion and novel pharmaceuticals, as strategies to reduce cardiometabolic risk in vulnerable and aging populations. Accordingly, his research is very closely aligned to National and International strategic health agendas focussed on reducing overall disease burden, including the World Health Organisation’s commitment to preventing and treating non-communicable disease across the globe.
Chris has built an international network of leading collaborators across science, healthcare, and industry, securing over £2.5 million in competitive research funding. He serves on multiple expert panels on physical activity and cardiometabolic health and is the Wales lead for the global May Measure Month blood pressure awareness campaign.
External positions
May Measure Month Lead for Wales
National Cardiovascular Research Network Committee
VascAgeNet / Artery Society: Research Working Groups
Youth Vascular Consortium
Multicenter Exercise Training Cures NAFLD Consortium (METCoN): Cofounder
Clinical Exercise Physiology UK: Standards & Education Work Group
Keywords
- RA0421 Public health. Hygiene. Preventive Medicine
- Exercise Physiology
- Cardiometabolic Disease
- Vascular Health
- Cardiorespiratory Fitness
- Exercise Training
- Lifestyle Intervention
- Healthy Ageing
Expertise related to UN Sustainable Development Goals
In 2015, UN member states agreed to 17 global Sustainable Development Goals (SDGs) to end poverty, protect the planet and ensure prosperity for all. This person’s work contributes towards the following SDG(s):
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SDG 3 Good Health and Well-being
Collaborations and top research areas from the last five years
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Acute measurement of flow-mediated dilation following passive heating in adults: The confounding role of altered shear stress and baseline vasodilation
Menzies, C., Clarke, N. D., Steward, C. J., Thake, C. D., Pugh, C. J. A. & Cullen, T., 16 Feb 2026, In: Physiological Reports. 14, 4, e70723.Research output: Contribution to journal › Article › peer-review
Open Access -
Cerebral blood velocity responses during and after sprint interval exercise in healthy young adults
Scott, E., Langson‐Justice, E., Smail, O., Lester, A. B., Oliveira, R., Pugh, C. J. A., Weston, M. E. & Bond, B. O., 1 May 2026, In: Physiological Reports. 14, 9Research output: Contribution to journal › Article › peer-review
Open Access -
Cohort Profile: The Youth Vascular Consortium
Park, J. Y., Kodithuwakku, V., Diaz, A., Pugh, C. J. A., Hanssen, H., Sinha, M. D., Fraenkel, E., Kim, H. C. & Climie, R. E., 6 Mar 2026, In: Artery Research. 32, 1, 7.Research output: Contribution to journal › Article › peer-review
Open Access -
Aerobic exercise interventions lead to MASH resolution in clinical trials: Pooled analysis using the MASH resolution index
Keating, S. E., Owen, P. J., Pugh, C. J. A., Cuthbertson, D. J. & Stine, J. G., 24 Mar 2025, In: Hepatology Communications. 9, 4, p. e0681 e0681.Research output: Contribution to journal › Article › peer-review
Open Access4 Citations (Scopus) -
Defining early vascular aging in youth: an expert consensus document from the youth vascular consortium
Kruger, R., Hersant, J., Kodithuwakku, V., Strauss-Kruger, M., Sinha, M. D., Johansson, M., Litwin, M., Hanssen, H., Königstein, K., Hidvégi, E. V., Stoner, L., Stone, K., Pugh, C. J. A., Mels, C. M. C., Breet, Y., Smith, W., Bia, D., Zócalo, Y., Diaz, A. & Khadilkar, A. & 6 others, , 21 May 2025, In: Journal of Hypertension. 43, 11, p. 1743-1749 7 p.Research output: Contribution to journal › Review article › peer-review
4 Citations (Scopus)