The effect of dietary antioxidants on levels of DNA damage in humans: a systematic review

Sophie Davies; Y.S.  Lee; R.M. Elliot

doi:10.1111/jhn.12535

The effect of dietary antioxidants on levels of DNA damage in humans: a systematic review

Sophie Davies
, Y.S. Lee
, R.M. Elliot

Allbwn ymchwil: Cyfraniad at gyfnodolyn › Cyfarfod Abstract › adolygiad gan gymheiriaid

Crynodeb

Oxidative stress is caused by an excess of reactive oxygen species (ROS) is associated with numerous chronic diseases, such as cardiovascular disease and cancer. The antioxidant hypothesis suggests that dietary antioxidants help protect tissue integrity by reducing cellular damage, including damage to DNA caused by ROS. Although protective findings are apparent in epidemiological studies which associate an increased amount of antioxidant-rich fruit and vegetables intake with a lower incidence of mortality, the strength of evidence from intervention studies is weak and inconsistent. The aim of the study was to analyse the effect of antioxidant supplementation on levels of DNA damage by conducting a systematic review of human randomised controlled trials (RCT).

Iaith wreiddiol	Saesneg
Tudalennau (o-i)	20-21
Nifer y tudalennau	1
Cyfnodolyn	Journal of Human Nutrition and Dietetics
Cyfrol	31
Rhif cyhoeddi	S1
Dynodwyr Gwrthrych Digidol (DOIs)	https://doi.org/10.1111/jhn.12535
Statws	Cyhoeddwyd - 1 Maw 2018
Cyhoeddwyd yn allanol	Ie
Digwyddiad	British Dietetic Association Research Symposium 2017 - Birmingham, Y Deyrnas Unedig Hyd: 6 Rhag 2017 → 6 Rhag 2017

NDC y CU

Mae’r allbwn hwn yn cyfrannu at y Nod(au) Datblygu Cynaliadwy canlynol

NDC 3 Iechyd a Llesiant Da

Mynediad at Ddogfen

10.1111/jhn.12535Trwydded: Free Access

Dyfynnu hyn

@article{57745ec13a12488aad956f945333d885,

title = "The effect of dietary antioxidants on levels of DNA damage in humans: a systematic review",

abstract = "Oxidative stress is caused by an excess of reactive oxygen species (ROS) is associated with numerous chronic diseases, such as cardiovascular disease and cancer. The antioxidant hypothesis suggests that dietary antioxidants help protect tissue integrity by reducing cellular damage, including damage to DNA caused by ROS. Although protective findings are apparent in epidemiological studies which associate an increased amount of antioxidant-rich fruit and vegetables intake with a lower incidence of mortality, the strength of evidence from intervention studies is weak and inconsistent. The aim of the study was to analyse the effect of antioxidant supplementation on levels of DNA damage by conducting a systematic review of human randomised controlled trials (RCT).",

author = "Sophie Davies and Y.S. Lee and R.M. Elliot",

year = "2018",

month = mar,

day = "1",

doi = "10.1111/jhn.12535",

language = "English",

volume = "31",

pages = "20--21",

journal = "Journal of Human Nutrition and Dietetics",

issn = "0952-3871",

number = "S1",

note = "British Dietetic Association Research Symposium 2017 ; Conference date: 06-12-2017 Through 06-12-2017",

}

TY - JOUR

T1 - The effect of dietary antioxidants on levels of DNA damage in humans

T2 - British Dietetic Association Research Symposium 2017

AU - Davies, Sophie

AU - Lee, Y.S.

AU - Elliot, R.M.

PY - 2018/3/1

Y1 - 2018/3/1

N2 - Oxidative stress is caused by an excess of reactive oxygen species (ROS) is associated with numerous chronic diseases, such as cardiovascular disease and cancer. The antioxidant hypothesis suggests that dietary antioxidants help protect tissue integrity by reducing cellular damage, including damage to DNA caused by ROS. Although protective findings are apparent in epidemiological studies which associate an increased amount of antioxidant-rich fruit and vegetables intake with a lower incidence of mortality, the strength of evidence from intervention studies is weak and inconsistent. The aim of the study was to analyse the effect of antioxidant supplementation on levels of DNA damage by conducting a systematic review of human randomised controlled trials (RCT).

AB - Oxidative stress is caused by an excess of reactive oxygen species (ROS) is associated with numerous chronic diseases, such as cardiovascular disease and cancer. The antioxidant hypothesis suggests that dietary antioxidants help protect tissue integrity by reducing cellular damage, including damage to DNA caused by ROS. Although protective findings are apparent in epidemiological studies which associate an increased amount of antioxidant-rich fruit and vegetables intake with a lower incidence of mortality, the strength of evidence from intervention studies is weak and inconsistent. The aim of the study was to analyse the effect of antioxidant supplementation on levels of DNA damage by conducting a systematic review of human randomised controlled trials (RCT).

U2 - 10.1111/jhn.12535

DO - 10.1111/jhn.12535

M3 - Meeting Abstract

SN - 0952-3871

VL - 31

SP - 20

EP - 21

JO - Journal of Human Nutrition and Dietetics

JF - Journal of Human Nutrition and Dietetics

IS - S1

Y2 - 6 December 2017 through 6 December 2017

ER -