Crynodeb
Preclinical development of human cells for potential therapeutic application in neurodegenerative diseases requires that their long-term survival, stability and functional efficacy be studied in animal models of human disease. Here we describe a strategy for long-term immune protection of human fetal and stem cell-derived neural cells transplanted into the adult rat brain, by desensitizing the host rat to similar cells in the neonatal period, without the need for additional immunosuppression.
Iaith wreiddiol | Saesneg |
---|---|
Tudalennau (o-i) | 271-273 |
Nifer y tudalennau | 3 |
Cyfnodolyn | Nature Methods |
Cyfrol | 6 |
Rhif cyhoeddi | 4 |
Dynodwyr Gwrthrych Digidol (DOIs) | |
Statws | Cyhoeddwyd - 8 Maw 2009 |
Cyhoeddwyd yn allanol | Ie |