Iliocaval Venous Obstruction, Cardiac Preload Reserve and Exercise Limitation

Rachael I. Morris*, Paul A. Sobotka, Peter K. Balmforth, Eric J. Stöhr, Barry J. McDonnell, Darren Spencer, Gerard J. O’Sullivan, Stephen A. Black

*Awdur cyfatebol y gwaith hwn

Allbwn ymchwil: Cyfraniad at gyfnodolynErthygl adolyguadolygiad gan gymheiriaid

15 Dyfyniadau (Scopus)

Crynodeb

Cardiac output during exercise increases by as much as fivefold in the untrained man, and by as much as eightfold in the elite athlete. Increasing venous return is a critical but much overlooked component of the physiological response to exercise. Cardiac disorders such as constrictive pericarditis, restrictive cardiomyopathy and pulmonary hypertension are recognised to impair preload and cause exercise limitation; however, the effects of peripheral venous obstruction on cardiac function have not been well described. This manuscript will discuss how obstruction of the iliocaval venous outflow can lead to impairment in exercise tolerance, how such obstructions may be diagnosed, the potential implications of chronic obstructions on sympathetic nervous system activation, and relevance of venous compression syndromes in heart failure with preserved ejection fraction.

Iaith wreiddiolSaesneg
Tudalennau (o-i)531-539
Nifer y tudalennau9
CyfnodolynJournal of Cardiovascular Translational Research
Cyfrol13
Rhif cyhoeddi4
Dynodwyr Gwrthrych Digidol (DOIs)
StatwsCyhoeddwyd - 10 Chwef 2020

Dyfynnu hyn