Exploring autonomic nervous system dysfunction in patients with cancer cachexia: A pilot study

Alpna Chauhan, Ashika Sequeria, Cathann Manderson, Matthew Maddocks, David Wasley, Andrew Wilcock*

*Awdur cyfatebol y gwaith hwn

Allbwn ymchwil: Cyfraniad at gyfnodolynErthygladolygiad gan gymheiriaid

19 Dyfyniadau (Scopus)

Crynodeb

Introduction: Abnormalities of the autonomic nervous system (ANS) have been associated with cachexia. Methods: In nine cancer patients who had lost weight and nine age-matched healthy volunteers heart rate variability (HRV) components were determined, together with serum cortisol and urinary catecholamines/metanephrines. Results: Compared to volunteers, patients exhibited a global reduction in HRV parameters, significantly so for high frequency, low frequency and total power (median values ms 2 103 vs. 313, 62 vs. 148 and 316 vs. 736 respectively, P<0.05). Biochemical values did not differ. Conclusion: Our results suggest the presence of ANS dysfunction in patients with cancer cachexia, with reduction in both sympathetic and parasympathetic components.

Iaith wreiddiolSaesneg
Tudalennau (o-i)93-95
Nifer y tudalennau3
CyfnodolynAutonomic Neuroscience: Basic and Clinical
Cyfrol166
Rhif cyhoeddi1-2
Dynodwyr Gwrthrych Digidol (DOIs)
StatwsCyhoeddwyd - 19 Hyd 2011

Dyfynnu hyn